2. GPCR/G Protein Neuronal Signaling
  3. MCHR1 (GPR24)
  4. MCHR1 antagonist 1

MCHR1 antagonist 1 is a selective antagonist of melanin concentrating hormone-1 (MCH1) receptor, with a Kb of 1 nM and a Ki of 4 nM at human MCH1, and may be used to reduce the body mass.

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MCHR1 antagonist 1 Chemical Structure

MCHR1 antagonist 1 Chemical Structure

CAS No. : 391610-37-0

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MCHR1 antagonist 1 Related Antibodies

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Description

MCHR1 antagonist 1 is a selective antagonist of melanin concentrating hormone-1 (MCH1) receptor, with a Kb of 1 nM and a Ki of 4 nM at human MCH1, and may be used to reduce the body mass.

IC50 & Target

Kb: 1 nM (Human MCH1)[1]
Ki: 4 nM (Human MCH1)[1]
In Vitro

MCHR1 antagonist 1 shows potent activities against melanin concentrating hormone-1 receptor, but less potent against human MCH1, NPY1, NPY5, GALR1, GALR2, GALR3, and rat 5HT2C receptors, with Kis of >50000 nM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

MCHR1 antagonist 1 Related Antibodies
Molecular Weight

557.59

Formula

C28H33F2N5O5
CAS No.
SMILES

O=C(C(C(C1=CC=C(F)C(F)=C1)N2C(NCCCN3CCC(C4=NC=CC=C4)CC3)=O)=C(COC)NC2=O)OC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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MCHR1 antagonist 1 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MCHR1 antagonist 1391610-37-0MCHR1 (GPR24)Melanin concentrating hormone receptor 1Inhibitorinhibitorinhibit

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